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KMID : 0978920190200020052
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Korean Journal of Clinical Geriatrics
2019 Volume.20 No. 2 p.52 ~ p.58
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Antithrombotic Therapy for Elderly Patients with Acute Coronary Syndrome
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Shim Min-Jung
Moon Jae-Youn
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Abstract
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Ischemic heart disease is the leading cause of death in older people. In particular, more than one-third of myocardial infarction patients are aged 75 or older. Nonetheless, little attention has been given to the scientific assessment of antithrombotic treatment of acute coronary syndrome in older people. Despite the fact that older people with acute coronary syndrome increases, most randomized trials of antithrombotic treatment of acute coronary syndrome have been conducted excluding this population. For now, there is no establishment of scientific practice guideline of antithrombic treatment of acute coronary syndrome in older people. In clinical decision-making process, concerns of drastic hemorrhagic complications in older people often override the benefits of antithrombic treatment and lead to pursue more passive conservative treatment. The present article reviews various antithrombotic agents with an emphasis on older people with acute coronary syndrome by most recent updates derived from clinical trials and future perspectives.
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KEYWORD
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Acute coronary syndrome, Anticoagulants, Elderly, Hemorrhage, Thrombosis
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